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Differences What are the advantages of each

Front view of Intel Xeon E5-2680

Reasons to consider the
Intel Xeon E5-2680

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Much more l3 cache 20 MB vs 8 MB 2.5x more l3 cache; more data can be stored in the l3 cache for quick access later
Significantly higher turbo clock speed 3.5 GHz vs 2.9 GHz More than 20% higher turbo clock speed
More threads 16 vs 8 Twice as many threads
Higher clock speed 2.7 GHz vs 2.6 GHz Around 5% higher clock speed
Much more l3 cache per core 2.5 MB/core vs 1 MB/core 2.5x more l3 cache per core
Much better overclocked clock speed (Air) 3.14 GHz vs 2.6 GHz More than 20% better overclocked clock speed (Air)
Much better overclocked clock speed (Water) 3.5 GHz vs 2.6 GHz Around 35% better overclocked clock speed (Water)
Front view of AMD Opteron 43GK HE

Reasons to consider the
AMD Opteron 43GK HE

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Much more l2 cache 8 MB vs 2 MB 4x more l2 cache; more data can be stored in the l2 cache for quick access later
Much lower typical power consumption 52.81W vs 105.63W 2x lower typical power consumption
Much more l2 cache per core 1 MB/core vs 0.25 MB/core 4x more l2 cache per core
Much lower annual commercial energy cost 56.94 $/year vs 113.88 $/year 2x lower annual commercial energy cost
Much lower annual home energy cost 15.66 $/year vs 31.32 $/year 2x lower annual home energy cost

Features Key features of the Xeon E5-2680  vs Opteron 43GK HE 

clock speed

Xeon E5-2680
2.7 GHz
Opteron 43GK HE
2.6 GHz

turbo clock speed

Xeon E5-2680
3.5 GHz
Opteron 43GK HE
2.9 GHz

L2 cache

L3 cache

overclocked clock speed (air)

Xeon E5-2680
3.14 GHz
Opteron 43GK HE
2.6 GHz

overclocked clock speed (water)

Xeon E5-2680
3.5 GHz
Opteron 43GK HE
2.6 GHz

Specifications Full list of technical specs

summary

Xeon E5-2680  vs
Opteron 43GK HE 
Clock speed 2.7 GHz 2.6 GHz
Turbo clock speed 3.5 GHz 2.9 GHz
Cores Octa core Octa core
Socket type
LGA 2011
C32

features

Has a NX bit Yes Yes
Has virtualization support Yes Yes
Instruction set extensions
SSE4a
AVX 1.1
SSE2
F16C
MMX
XOP
AVX
SSE3
SSE
CLMUL
AMD64
SSE4.1
FMA4
FMA3
SSE4.2
CVT16
AMD-V
Supplemental SSE3
AES
Supports dynamic frequency scaling Yes Yes

memory controller

Memory controller Built-in Built-in
Channels Quad Channel Dual Channel
Supports ECC Yes Yes

details

Xeon E5-2680  vs
Opteron 43GK HE 
Threads 16 8
L2 cache 2 MB 8 MB
L2 cache per core 0.25 MB/core 1 MB/core
L3 cache 20 MB 8 MB
L3 cache per core 2.5 MB/core 1 MB/core
Manufacture process 32 nm 32 nm
Max CPUs 2 2
Clock multiplier 35 13

overclocking

Overclocked clock speed 3.14 GHz 2.6 GHz
Overclocked clock speed (Water) 3.5 GHz 2.6 GHz
Overclocked clock speed (Air) 3.14 GHz 2.6 GHz

power consumption

TDP 130W 65W
Annual home energy cost 31.32 $/year 15.66 $/year
Annual commercial energy cost 113.88 $/year 56.94 $/year
Typical power consumption 105.63W 52.81W

bus

Architecture QPI HyperTransport 3.0
Transfer rate 8,000 MT/s 6,400 MT/s
Clock speed 4,000 MHz 3,200 MHz
Intel Xeon E5-2680
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AMD Opteron 43GK HE
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